Diverse types of antibacterial agents (curcumin, Ag nanoparticles and antimicrobial peptide KR-12) were separately encapsulated in RSFPF127 to endow it with antibacterial activity.
Different pluronic polymers were introduced to optimize its mechanical property, and the RSF film with 2.5% Pluronic F127 (RSFPF127) stood out due to the satisfied mechanical property, hydrophilicity and transmittance to address these issues.
The clinical application of regenerated silk fibroin (RSF) film for wound treatment is restricted by the undesirable mechanical properties and a shortage of antibacterial ability.
